Caleva Blog

CML, VDE

How do I decide which laboratory extruder and spheronizer I need?

We are often asked for advice by researchers and teachers who want to acquire laboratory equipment for the development of both formulations and processes using the techniques of Extrusion and Spheronization in the laboratory.  All users are individual and have different requirements and there is not a single system that will fit all needs.

Find out what you need to consider.

 

Extrusion of small batches

The Caleva Multi-Lab (CML) can Mix/Granulate, Extrude and Spheronize all in one base unit.

This article is about the Extruder attachment that comes with the CML.

The Multi-lab is capable of working with a variety of materials from catalysts and pharmaceuticals, to agricultural products.

The Extruder

The extrusion attachment on the CML is in the form of a single screw Extruder. A variety of...

Mixing and granulating small batches

The Caleva Multi-Lab (CML) is capable of performing 3 different processes: Mixing, Extrusion and Spheronization.

This article is about the mixing and granulation phase of the process.

The multi-lab works with a large range of materials from pharmaceutical materials and catalysts, to agricultural products.

The granulator/mixer

The mixer attachment blades thoroughly mix the liquid binder with...

Mix, Extrude & Spheronize in a single base - watch a video

Call Caleva's friendly team to talk about this unique solution for your applications, whatever your challenges are.

 

The Caleva Multi-Lab (CML) is often considered to be the flagship of Caleva lab equipment.

Being able to perform 3 different processes rapidly in one machine with a footprint just slightly larger than an A3 piece of paper, makes the CML a welcome addition to any lab space that...

The Caleva Family of Laboratory Equipment

Whilst you may have heard of Caleva and any one of its flagship pieces of equipment, we'd like to introduce you to the family of Caleva laboratory equipment that you may find helpful for your application in your industry sector.  Choose one process or choose all of them.  Select further functions as you need them.  This adaptable and future proof suite of equipment will allow you to obtain...

Caleva Multi Lab & Bone Regeneration study Medical University Gdańsk

Drug-loaded mesoporous silica/calcium phosphate composites for bone regeneration

Adrian Szewczyk at Department of Physical Chemistry, Faculty of Pharmacy, Medical University of Gdańsk has kindly allowed us to introduce this paper that introduces a study of Drug-loaded mesoporous silica/calcium phosphate composites for bone regeneration.  

 

Caleva Multi Lab at SATC Brazil

The Caleva Multi Lab had been directly recommended by the National Energy Technological Laboratory (NETL - part of the U.S. Department of Energy (DOE)) (https://www.netl.doe.gov/about) - the NETL also have a well regarded Caleva Multi Lab.

We worked through the established Caleva Training Programme with the CML and then related this to SATC's own products.  In addition to the researchers there...

Caleva Mixer working in catalyst application for Ethylene and Propylene

Components were mixed with a specialist Caleva mixer to form a homogeneous paste

How can I be sure that the trials and development work that I do will give me comparable results when I need to scale up to production sizes?

Scale up of the spheronization process is relatively well known and understood. All of the Caleva extrusion and spheronization equipment is designed with scale up in mind.Our range of screw extruders have the ability to modify the density of your extrudate when this is important.
  • The smallest extruder we offer is the Caleva Multi Lab (CML) with an extruder attachment designed to work with...

New installation at Tupras oil refinery in Turkey

A great few days spent at Tupras installing our Mixer Torque Rheometer and Caleva Multi Lab machines in their R&D Laboratories.

Tupras (Turkish Petroleum Refineries Corp) in Kocaeli is Turkey’s only oil refiner, operating four refineries with a total capacity to handle an annual 28.1 million tons of crude per year.

Extrusion–spheronization a promising pelletization technique: In-depth review

Abstract

This review article deals with various aspects of the extrusion–spheronization technique. The first part includes different steps in the production process of pellets such as granulation, extrusion, spheronization, and drying. In the second part, the parameters which can influence the quality of pellets including formulation (moisture content, granulating liquid, excipients, and...

Catalyst Pellets cracked! The strange apple sauce method

Over the past couple of years I have worked with a huge number of chemical engineering teams, trying to crack the optimum base for a catalyst pellet. After hours of trials and research, I am pleased to say, we’ve done it!

Alejandro Lopez from Applied Materials Science, Uppsala University visits Caleva for training on the Caleva Multi Lab

In June 2016 our friend and customer Alejandro Lopez from the Division of Applied Materials Science, Uppsala University visited Caleva in the UK for training and testing of their newly purchased Caleva Multi Lab. The Department have all of the Multi Lab attachments, the screw extruder assembly, spheronizer and high viscosity mixing attachment - the mixer attachment which includes a high...

Caleva Install a Multi Lab for Catalyst Research at the University of Porto - Departamento de Engenharia Quimica

Aaron Quinn from Caleva, working with teaching staff at the University of Porto, Chemical Engineering Department (Departamento de Engenharia Química).

Caleva installation and training for new Caleva Multi Lab at University of Durham

Aaron Quinn met with Laboratory Technicians Hannah Rigby and Alison Bradley and Lecturer in Pharmaceutics, Dr David Berry at the School of Medicine to assist with the installation and testing of the new Caleva Multi Lab for the University of Durham.  Aaron also provided additional training in the use of the equipment, including how to attach and set up the various tools - the...

Pharmacy Students from University of Reading visit Caleva’s Laboratory

We were delighted to welcome Akhil and Mohammed to our laboratory in the UK for training on our laboratory equipment. They both worked with the Mini Coater Drier and Mixer Torque Rheometer as well as the Caleva Multi Lab. It was an enjoyable day for all and we appreciate their visit and they are welcome to visit us again in the future. Indeed, if any pharmacy student would like to come and...

Medical University of Gdansk visit Caleva

 

University of Reading

Caleva are very happy to report that the extrusion and spheronization (and tablet coating) equipment installed at the University of Reading by Dr Steve Robinson is proving to be a great success. Associate Professor, Dr Alex Edwards, confirms

Visit Caleva at the CRS Conference - 2015 July 26-29

This year is the 42nd annual CRS conference and exposition. It showcases technology, products, and services for the pharmaceutical industry from organisations around the world. The 2015 Annual Meeting this year is in Edinburgh, Scotland, at the EICC.

Talk to us at Achema

This year the ACHEMA 2015 – World Forum and 31, widely known as the leading show for the chemical engineering and process industries, will take place from 15 – 19 June 2015 – Frankfurt am Main, Germany. The show is generally busy and full of interesting new technologies and is one of the most respected world forums for the chemical engineering and process industries.