• Do you have heat generation and associated issues with your Extrusion process?

    Do you have heat generation and associated issues with your Extrusion process?

    When talking with customers who manage production scale extrusion I am often asked to comment on the amount of heat generated and the issues that this can cause.  In reality it is just something that we have to live with as all extrusion processing will generate heat.  The amount of heat generated will vary depending on the formulation of the product, the rate of extrusion, the physical specifications of the extruder and the type of extruder being used (screw, gear or basket are the common ones).

  • Aaron Quinn from Caleva discusses which extrusion die do I need?

    What size extrusion die plate do I need?

    I am always asked, ‘what sized die plate do I need’ for a certain diameter of pellet.  The higher the water content, the higher percentage of shrinkage upon drying, thus meaning a 1mm wet pellet , may decrease in size by up to 30% when dry.  However, a formulation with a lower level of water content, mixed with a variety of excipients and additives can see a much smaller percentage shrinkage.

  • Caleva apple sauce method for catalyst pellet preparation

    Catalyst Pellets cracked! The strange apple sauce method

    Over the past couple of years I have worked with a huge number of chemical engineering teams, trying to crack the optimum base for a catalyst pellet. After hours of trials and research, I am pleased to say, we’ve done it!  The benefit of using CMC is that it will retain the water content required for the spheronization process. You can later burn this off, leaving the pure catalyst pellets for further testing and development.

  • Ms Tuyen of Pharmacy Faculty Can Tho University Vietnam discusses the Caleva Mini Coater Drier with Mr Nguyen Hung

    Caleva visits staff from Pharmacy Department Can Tho University, Vietnam

    Can Tho University in southern Vietnam are using a Caleva Mini Coater Drier (MCD-2) for teaching pharmacy students and for their research projects.   The unit is also provided for research to an outside organisation for their formulation development. The objective of the visit to Can Tho was to ensure that everything is going well and that there were no questions or issues that need addressing.  Can Tho University students and academic staff regularly use their Caleva Mini Coater Drier and it is runs efficiently and without any issues.  

  • pellet spillage after spheronization at Caleva - Aaron will know what to do

    Spheronization Barrier Technique from Caleva

    A tip from spheronization expert Aaron Quinn.  Stop the machine, squeeze between your fingers a small amount of your extruded material and stick it to the side wall of the spheronizer drum. Then turn it on.  The addition of this slight barrier  has an instant impact causing the material to break and start to spheronize in the normal way. 

  • Extruded citrus meal for leaf cutting ant pest control in Costa Rica

    A visitor to Caleva uses innovative Caleva technology to help investigations into the control of leaf cutting ants in Costa Rica

    Ms Catherine Jimenez from the Laboratorio do Biotechnologia, Universidad de Costa Rica is working in collaboration with a company to produce a novel ant bait for use against a major agricultural pest.  The requirements for the study was to have available a laboratory extruder that would be able to produce extrudate not only of different diameters but also of different densities.

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