Back

Mixer Torque Rheometer used with Food Powders

Research Article University of Padova where their Caleva Rheometer was used

By Andrea Newton
21 Apr 2020 in Mixer Torque Rheometer, University Padova

Leave A Comment

 

 

 

Talk To Caleva

The Caleva Family of Laboratory Equipment

Whilst you may have heard of Caleva and any one of its flagship pieces of equipment, we'd like to introduce you to the family of Caleva laboratory equipment that you may find helpful for your application in your industry sector.  Choose one process or choose all of them.  Select further functions as... Read More

PharmaTeG purchase a Caleva Mixer Torque Rheometer MTR3

  PharmaTeG – Pharmaceutical Technology Group - is founded by a group of pharmaceutical technologists belonging to the Department of Pharmaceutical and Pharmacological Science and School of Hospital Pharmacy, University of Padova, Italy. The group collaborates with the Industrial Engineering Departm... Read More

Inconsistent spheronization results with difficult active ingredient?

The following case study demonstrates how the Caleva Mixer Torque Rheometer.  The MTR-3 was an invaluable aid in a specific case. A manufacturer of generic Venlafaxine pellets was experiencing inconsistent results from their manufacturing line. The resultant product was variable in both usable yield... Read More

Mixer Torque Rheometer used with Food Powders

Research Article University of Padova where their Caleva Rheometer was used   Abstract Vegetable soups are complex mixtures containing vegetables in different percentages, thickeners, salt, fat, and emulsifying/wetting agents. When prepared as dehydrated powders in convenience foods, they need to be... Read More

Caleva visit to Sandoz for an MTR install

Last week, Scott and Steve represented Caleva, by travelling to India to meet Our long standing distributor for the region, GDI. With Hirak and Prasanta from GDI, they attended meetings, gave presentations and performed an installation and training session of the MTR-3 for Sandoz, a company which is... Read More

The Importance of End Point Detection Consistency

This world is not only for us. Can you imagine world had no animals, what would it be like? Would the trees be green? Without birds or squirrels, less trees would grow. There would be no pets, no flowers and no bees. If even one part of our ecosystem is removed, we will all die. Without animals, we ... Read More

Caleva Multi Lab & Bone Regeneration study Medical University Gdańsk

Drug-loaded mesoporous silica/calcium phosphate composites for bone regeneration Adrian Szewczyk at Department of Physical Chemistry, Faculty of Pharmacy, Medical University of Gdańsk has kindly allowed us to introduce this paper that introduces a study of Drug-loaded mesoporous silica/calcium phosp... Read More

Agglomeration properties of gluten-free flours under water addition and shearing conditions

The different states of agglomeration were identified by the evolution of rheological properties under water addition and shearing conditions using a Caleva® mixer torque rheometer.  Read More

How reproducible can measurements be of something that is not homogeneous?

The MTR-3 uniquely offers a means of characterising the rheological properties of a wet granulation by providing a quantitative value of the consistency of the material tested. The more traditional hand squeeze test, previously widely used, to measure or compare granulations, is falling into disrepu... Read More

Yield problems in production and quality control

One of the strengths of the Caleva Mixer Torque Rheometer (MTR-3) is that it can be used to verify the properties of wet powder mass samples taken during production in large scale mixer/granulator systems. It can be used simply as a quality control tool on a regular basis or specifically as an aid t... Read More

How the Mixer Torque Rheometer resolved a tablet friability issue

Caleva worked closely with a well known producer of food supplements made from natural materials, plant extracts and other natural food sources.  Their tablet formulations work well and this nutraceutical company has a good reputation for their products.  Generally they do not encounter problems wit... Read More

Determination of moisture requirement to prepare spheroids by extrusion-spheronization

Spheroids are popularly used in the design of multi-particulate drug delivery systems. Extrusion and spheronization is commonly employed to manufacture spheroids in the pharmaceutical industry. It is a multiple-step manufacturing process which could be summarized into the flow chart as shown in Figu... Read More

Save Time and Cost in Formulation Development

In the mid 1990’s, the field of pyrotechnics was limited mainly to applications in aircraft ordnance, fireworks and rock blasting. This has been developed to a highly advanced science and is an extensively used technology which finds application in spacecraft, aircraft and underwater vehicle systems... Read More

"End Point Determination” Using the Caleva Mixer Torque Rheometer

A company wished to move a formulation currently undergoing product development from small scale laboratory (with batches of 50 grams) to the next stage for a larger scale batch trial of 100 kg (scale–up).  The development had been started using a small Caleva Multi Lab bench top mixer (maximum batc... Read More

Pharmacy Students from University of Reading visit Caleva’s Laboratory

We were delighted to welcome Akhil and Mohammed to our laboratory in the UK for training on our laboratory equipment. They both worked with the Mini Coater Drier and Mixer Torque Rheometer as well as the Caleva Multi Lab. It was an enjoyable day for all and we appreciate their visit and they are wel... Read More

Caleva Mixer Torque Rheometer - The importance of mixing time for your formulation development and production

It is well established and understood that one of the most important factors in the development of a formulation for both tableting and making pellets by extrusion and spheronization is the amount of liquid binder added to the formulation. What is less widely acknowledged is the importance of mixing... Read More

Caleva Visit to GPO in Thailand on 27th March 2013

he Thai GPO (Government Pharmaceutical Organisation) based in Bangkok has been a user of Caleva bench-top extruders and spheronizers as well as the Caleva Mixer Torque Rheometer for many years.   A meeting was held to discuss on-going work to see if any of the formulations developed in the laborator... Read More