Drug-loaded mesoporous silica/calcium phosphate composites for bone regeneration
Adrian Szewczyk at Department of Physical Chemistry, Faculty of Pharmacy, Medical University of Gdańsk has kindly allowed us to introduce this paper that introduces a study of Drug-loaded mesoporous silica/calcium phosphate composites for bone regeneration.
The pellets were obtained in the laboratory scale using the wet-granulation, extrusion and spheronization method. The pellets proved satisfactory mechanical properties which allowed for further investigations (the drug release studies and the mineralization potential assay) without a risk of pellets cracking. The extrusion and spheronization was done using the Caleva Multi Lab and the binder addition required was determined by the Caleva Mixer Torque Rheometer.
The full article can be found here http://yadda.icm.edu.pl/yadda/element/bwmeta1.element.baztech-f72ed0f9-0652-4263-a85b-5d5105c435fc