Spheronization and Spheronizers - A general overview of the manufacture of spheroids (pharmaceutical pellets)

The manufacture of pharmaceutical pellets by Spheronization (Spheronisation or Marumerization) with Spheronizers

Caleva Process Solutions has designed and manufactured production and laboratory R&D  spheronizers for more than 40 years.

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Amongst the advantages of spheronisation (pelletisation) for the pharma industry
are:-

• Manufacture of modified release solid dose formulations.
• The easy formulation and mixing of otherwise incompatible formulations.
• To enable uniform coating and accurate free flow filling into capsules drug applications within the pharmaceutical industry require consistent smooth surface particles, with a narrow size distribution.
• To offer dust free packaging. Handling and use can be important marketing and product features within the pharmaceutical, food and cosmetic industries.
• To eliminate of dust within the agro-chemical, pigment, and catalyst industries. This can reduce risk due to toxic, environmental, and explosive hazards.
• To improve processing consistency and productivity by using consistent free-flowing product
• To reduce product settlement in transport by spheronization of powder products prior to packaging.